Description of target: Polycomb group (pcg) protein. catalytic subunit of the prc2/eed-ezh1 complex, which methylates 'lys-27' of histone h3, leading to transcriptional repression of the affected target gene. able to mono-, di- and trimethylate 'lys-27' of histone h3 to form h3k27me1, h3k27me2 and h3k27me3, respectively. required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. compared to ezh2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming h3k27me3, which is required for embryonic stem cell identity and proper differentiation.;Species reactivity: Mouse;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: <0.061ng/mL
5311.49RON
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Număr Catalog 247-OKDD00828CategorieAfaceri și industrie > Știință și laboratorFurnizorAviva Systems BiologyGentaurDimensiune96 WellsTipsingle