Tropomyosin Alpha Polyclonal Anti... Jiaxing Korain Biotech Ltd (B...

Tropomyosin Alpha Polyclonal Antibody

TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The tropomyosin alpha-1 chain is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

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Număr Catalog 772-BT-AP09222-100ul

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune100ulTipsingle

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20/08/2026

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