LTK is a member of the ros/insulin receptor family of tyrosine kinases. LTK express a gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain and it may encode a signal transduction subunit for one or more of the hematopoietic receptors . LTK gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions . LTK causes upregulation of the PI3K pathway and possibly form a genetic component of susceptibility to abnormal proliferation of self-reactive B cells in SLE (3).
1657.6RON
În stoc
Număr Catalog 10021-Z500201CategorieAfaceri și industrie > Știință și laboratorFurnizorABMGentaurDimensiune10 µgTipsingle