Glucocorticoid receptor is a protein encoded by the NR3C1 gene which is approximately 85,6 kDa. The glucocorticoid receptor is localised to the cytoplasm, mitochondrion and nucleus. It is involved in PEDF induced signalling, gene expression and the nuclear receptor transcription pathway. It is a protein which can function both as a transcription factor that binds to glucocorticoid response elements to activate their transcription, and as a regulator of other transcription factors. The glucocorticoid receptor is widely expressed. Mutations in the NR3C1 gene may result in glucocorticoid resistance. STJ97101 was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. This antibody detects endogenous GR proteins.
1059.07RON
În stoc
Număr Catalog 665-STJ97101CategorieAfaceri și industrie > Știință și laboratorFurnizorSt John's LaboratoryGentaurDimensiune200 µlTipsingle