N-cadherin is a protein encoded by the CDH2 gene which is approximately 99,8 kDa. N-cadherin is localised to the cell membrane. It is involved in cell junction organization, ERK signalling, blood-brain barrier and immune cell transmigration. It is a calcium-dependent cell adhesion protein. They interact with themselves in a homophilic manner in connecting cells which contribute to the sorting of heterogeneous cell types. It also acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone. N-cadherin is expressed in the nervous system, liver, muscle, heart and eye. Mutations in the CDH2 gene may result in malignant pleural mesothelioma and hypoplastic left heart syndrome. STJ94353 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of N-cadherin protein.
1059.07RON
În stoc
Număr Catalog 665-STJ94353CategorieAfaceri și industrie > Știință și laboratorFurnizorSt John's LaboratoryGentaurDimensiune200 µlTipsingle
