Description of target: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine (PubMed:2176511). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Plays a role in cellular responses to ethanol.By similarity
 <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p>
 
 
 <p><a href="/manual/evidences#ECO:0000250">More…</a></p> Manual assertion inferred from sequence similarity toiUniProtKB:P23416 (GLRA2_HUMAN)1 Publication
 <p>Manually curated information for which there is published experimental evidence.</p>
 
 
 <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.1"A single amino acid exchange alters the pharmacology of neonatal rat glycine receptor subunit."_x005F_x005F_x000D_Kuhse J., Schmieden V., Betz H._x005F_x005F_x000D_Neuron 5:867-873(1990) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA-2*), FUNCTION, SUBCELLULAR LOCATION, ENZYME REGULATION, DEVELOPMENTAL STAGE, VARIANT GLY-194, CHARACTERIZATION OF VARIANT GLY-194. ;Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.115 ng/mL
4816.9RON
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Număr Catalog 247-OKCD00952CategorieAfaceri și industrie > Știință și laboratorFurnizorAviva Systems BiologyGentaurDimensiune96 WellsTipsingle
