Description of target: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.1 Publication
 <p>Manually curated information for which there is published experimental evidence.</p>
 
 
 <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.9"NMR structures of the transmembrane domains of the alpha4beta2 nAChR."_x005F_x005F_x000D_Bondarenko V., Mowrey D., Tillman T., Cui T., Liu L.T., Xu Y., Tang P._x005F_x005F_x000D_Biochim. Biophys. Acta 1818:1261-1268(2012) [PubMed] [Europe PMC] [Abstract]Cited for: STRUCTURE BY NMR OF 234-484, SUBUNIT, FUNCTION. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.054 ng/mL
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Număr Catalog 247-OKCD00280CategorieAfaceri și industrie > Știință și laboratorFurnizorAviva Systems BiologyGentaurDimensiune96 WellsTipsingle