Belnacasan (VX-765) is an orally bioactive proagent of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1β and IL-18 by human PBMCs with an IC50 of ~0.7 μM[1][2].
1454.57RON
În stoc
Număr Catalog 804-HY-13205CategorieAfaceri și industrie > Știință și laboratorFurnizorMedChemExpressGentaurDimensiune50mgTipsingle