Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc2Man9GlcNAc2 oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia. This protein is involved in the pathway N-glycan metabolism, which is part of Glycan metabolism. View all proteins of this organism that are known to be involved in the pathway N-glycan metabolism and in Glycan metabolism. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.
1034.88RON
În stoc
Număr Catalog 992-HA720042CategorieAfaceri și industrie > Știință și laboratorFurnizorHUABIOGentaurDimensiune100ulTipsingle