Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor| known as kinase insert domain receptor| is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation| survival| migration| tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors| including Rab GTPase| P2Y purine nucleotide receptor| integrin alphaVbeta3| T-cell protein tyrosine phosphatase| etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
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Număr Catalog 772-BT-AP13436-20ulCategorieAfaceri și industrie > Știință și laboratorFurnizorJiaxing Korain Biotech Ltd (BT Labs)GentaurDimensiune20ulTipsingle