This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue| encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity| suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation| senescence| tumor suppression| cell growth control| and chemotaxis to each member of the family.
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Număr Catalog 772-BT-AP11100-20ulCategorieAfaceri și industrie > Știință și laboratorFurnizorJiaxing Korain Biotech Ltd (BT Labs)GentaurDimensiune20ulTipsingle