This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation| a PTK domain| and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs| respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles| and binds to cell surface receptors| including CD4 and CD8| and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.
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Număr Catalog 772-BT-AP06913-100ulCategorieAfaceri și industrie > Știință și laboratorFurnizorJiaxing Korain Biotech Ltd (BT Labs)GentaurDimensiune100ulTipsingle