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MTA1 Polyclonal Antibody
MTA1 (metastasis associated 1) encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of MTA1 has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for MTA1.

Cerere de ofertă

La cerere
Număr Catalog 772-BT-AP05639-100ul
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune100ulTipsingle
Produse asociate
MTA1 Polyclonal Antibody
749-ABP56961-003ml
0.03ml
849.41 RON
MTA1 Polyclonal Antibody
749-ABP56961-01ml
0.1ml
1553.66 RON
MTA1 Polyclonal Antibody
749-ABP56961-02ml
0.2ml
2225.66 RON
MTA1 Polyclonal Antibody
544-MBS8570762-01mLAF405S
0.1mL(AF405S)
2531.2 RON
OABB00437-100UG - MTA1 Polyclonal Antibody
247-OABB00437-100UG
100ug
1877.12 RON
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